A CASE OF A 61 YEAR OLD MAN WITH BICYTOPENIA UNDER EVALUATION
A 61 year old male resident of Ramulapeta,yadadri dist who is a daily wage labourer in construction work came to the hospital with complaint of
CHIEF COMPLAINTS
Dry cough since 10 days
Dragging pain towards the finger tips since 10 days
Lower back pain since 10 days
Shortness of breath Grade 2 -grade 3
Chest pain near heart since 10 days
HISTORY OF PRESENTING ILLNESS
PATIENT WAS APPARENTLY ASYMPTOMATIC 3 YEAR AGO WHEN
He noticed involuntary movements of upper right limb at rest and decreased on movement
2 years ago his wife passed away because of which he became reclusive and increased intake of alcohol
1 year back he noticed showing of moments and decrease in his pitch of voice
He has used medication but stopped using after 5 months due to lack of improvement of symptoms
Since 20 days back he has trouble recollecting and takes at least 30-40 minutes if he wants to do something
Like bringing a article from home
Then 10 days back he experienced dry cough
Lower back pain on both sides draging type radiating towards the coccyx
Parn in upper right arm radiating towards the finger tips dragging in nature
Both of which were relieved on medication and rest
Chest pain more of a burning sensation since 10 days
Shortness of breath Grade 2 -3
Not relieved on rest
No association with vomiting or headaches
PAST HISTORY
10 days back had a episode of fever which subsided on medication
Not a known case of
Diabetes
Hypertension
Tb
Asthama
Epilepsy
Cvd
Chemotherapy
FAMILY HISTORY
Not significant
PERSONAL HISTORY
Diet - mixed
Appetite - Decreased
Bowel and bladder - adequate
Allergies -no
Addiction - after demise of wife he sought these
18 ciggarette per day and alcohol
Daily routine before 10 days
5:00 woke up
6-7:00 had breakfast
9:30 went to work
1:00 lunch
6:30_7:00 comes back and watches tv
8-9:00 dinner
9:30 sleep
Daily routine after pain
Stopped going to work
Still wakes up at 5 but then
Eats and sleeps
Sometimes watches tv
GENERAL EXAMINATION
Thin built and malnourished
Vitals
Temperature : Afebrile
Pulse: 81
BP:110/80 mm/ hg
RR :18
SPO2 : 97%
Pallor : present
Icterus present
Clubbing absent
Cyanosis absent
Lymphadenopathy absent
Pedal edema absent
JVP RAISED
SYSTEMIC EXAMINATION
CVS
Apex beat 6 th intercoastal space
No thrills
S1 S2 heard
No murmurs
RESPIRATORY SYSTEM
No dyspnoea wheeze
Central trachea
Bilateral air entry +
Bilateral basal crepts +
ABDOMEN
Soft
Non tender
CNS
Higher functions
Patient is conscious, coherent,and co operative
Patient is oriented to place not to time and person
Delay in response but able to recall
Crainal nerve intact
Examination of motor system
Tone increased on right upper limb
Not able to approximate both upper limbs
Power of muscle normal
Coordination of movement
Tremors : resting
pill rolling movement
Reflex
Sensory system
Normal
INVESTIGATION
Day 1
Day 3
Day 4
Day 5
Day 6
Day 7
Day 8
Day 9
Peripheral blood smear on 8th
Peripheral blood smear on 10th
Peripheral blood smear On 11th
PROVISIONAL DIAGNOSIS
BICYTOPENIA SECONDARY TO PLASMA CELL DYSCRACIA
WITH
COMMUNITY ACQUIRED PNEUMONIA WITH (BILATERAL LOWER LOBE CONSOLIDATION)
WITH
MODERATE HEPATOSPLEENOMEGALY
WITH
HYPONATREMIA (RECOVERED )2 TO SIADH?
ALTERED MENTATION
Day 1
S :-
Patient is having resting tremors
Delayed speech
Altered sensorium
O:-
Pt is conscious, coherent cooperative
Bp:-140/70
Pr:-92 bpm
Cvs:-s1s2+
R/s:-BLAE +
P/A:- soft , non tender spleenomegaly
CNS:- NAD
A:-
BICYTOPENIA UNDER EVALUATION
WITH
COMMUNITY ACQUIRED PNEUMONIA WITH PARKINSON'S(?)WITH
MODERATE SPLEENOMEGALY
P:-
Inj AUGMENTIN 1.2g/IV/BD
TAB AZITHROMICIN 500 mg/PO/OD
INJ OPTINEURON 1 amp 100 ml /NS
Vital monitoring
Temperature monitoring
Day 2
S :-
Patient is having resting tremors
Delayed speech
O:-
Pt is conscious, coherent cooperative
Bp:-120/70
Pr:-93 bpm
Cvs:-s1s2+
R/s:-BLAE +
P/A:- soft , non tender spleenomegaly
CNS:- NAD
A
BICYTOPENIA UNDER EVALUATION
WITH
COMMUNITY ACQUIRED PNEUMONIA WITH PARKINSON'S(?)WITH
MODERATE SPLEENOMEGALY
P:-
Inj AUGMENTIN 1.2g/IV/BD
TAB AZITHROMICIN 500 mg/PO/OD
INJ M6RVIG6M1000 micrograms//IV/OD IN 50 ML NS
INJ OPTINEURON 1 amp 200 ml /NS
Vital monitoring
Temperature monitoring
Day 3
S :-
Patient is having resting tremors
Delayed speech
O:-
Pt is conscious, coherent cooperative
Bp:-110/80
Pr:-86 bpm
Cvs:-s1s2+
R/s:-BLAE +
P/A:- soft , non tender spleenomegaly
CNS:- NAD
A:-BICYTOPENIA UNDER EVALUATION
WITH
COMMUNITY ACQUIRED PNEUMONIA WITH PARKINSON'S(?)WITH
MODERATE SPLEENOMEGALY
P:-
Inj AUGMENTIN 1.2g/IV/BD
TAB AZITHROMICIN 500 mg/PO/OD
INJ M6RVIG6M1000 micrograms//IV/OD IN 50 ML NS
TAB PANTOPRAZOLE 40 MG/PO/OD
Vital monitoring
Temperature monitoring
Day 4
S :-
Patient is having resting tremors
Delayed speech
O:-
Pt is conscious, coherent cooperative
Bp:-110/80
Pr:-86 bpm
Cvs:-s1s2+
R/s:-BLAE +
P/A:- soft , non tender spleenomegaly
CNS:- NAD
A:-BICYTOPENIA UNDER EVALUATION
WITH
COMMUNITY ACQUIRED PNEUMONIA WITH PARKINSON'S(?)WITH
MODERATE SPLEENOMEGALY
P:-
Inj AUGMENTIN 1.2g/IV/BD
TAB AZITHROMICIN 500 mg/PO/OD
INJ M6RVIG6M1000 micrograms//IV/OD IN 50 ML NS
TAB PANTOPRAZOLE 40 MG/PO/OD
Vital monitoring
Temperature monitoring
Day 5
S :-
Patient is having resting tremors
Fever spikes
Shortness of breath
Pain at bone marrow biopsy site
Delayed speech
O:-
Pt is conscious, coherent cooperative
Bp:-110/70
Pr:-92 bpm
Cvs:-s1s2+
R/s:-BLAE +
P/A:- soft , non tender spleenomegaly
CNS:- NAD
A:-BICYTOPENIA UNDER EVALUATION(2 to malignancy infection)
WITH
COMMUNITY ACQUIRED PNEUMONIA WITH ESSENTIAL TREMORS WITH
MODERATE SPLEENOMEGALY
P:-
TAB AZITHROMICIN 500 mg /PO/OD
TAB ULTRACET1/2tab /QID
TAB PANTOPRAZOLE 40 MG/PO/OD
INJ PIPTAS 4.5gm /IV/TID
TAB ZINCOVIT OD/PO
Vital monitoring
Temperature monitoring
Day 6
S :-
Patient is having resting tremors
Pain at bone marrow biopsy site
Delayed speech
O:-
Pt is conscious, coherent cooperative
Bp:-120/80
Pr:-98 bpm
Cvs:-s1s2+
R/s:-BLAE +
P/A:- soft , non tender spleenomegaly
CNS:- NAD
A:-BICYTOPENIA UNDER EVALUATION(2 to malignancy infection)
WITH
COMMUNITY ACQUIRED PNEUMONIA WITH ESSENTIAL TREMORS WITH
MODERATE HEPATOSPLEENOMEGALY
P:-
TAB DOLO 650 mg /PO/OD
TAB ULTRACET1/2tab /QID
TAB PANTOPRAZOLE 40 MG/PO/OD
INJ PIPTAS 4.5gm /IV/TID
TAB ZINCOVIT OD/PO
Vital monitoring
Day 7
S :-
Patient is having resting tremors
Altered behavior GCS E4V4M4
Involuntary Micturation
Fever spikes
Pain at bone marrow biopsy site
Delayed speech
O:-
Pt is conscious
Bp:-110/60
Pr:-130 bpm
Cvs:-s1s2+
R/s:-BLAE +
P/A:- soft , non tender spleenomegaly
CNS:- NAD
A:-BICYTOPENIA UNDER EVALUATION(2 to malignancy infection)
WITH
COMMUNITY ACQUIRED PNEUMONIA WITH ESSENTIAL TREMORS WITH
MODERATE HEPATOSPLEENOMEGALY
P:-
Riley's tube
Foleys catheter
IVF 3% Nacl at 10ml/hr
INJ MEROPENUM 1g IV STAT
INJ MEROPENUM 1g IV/BD
Temperature charting
Vital monitoring
Ryles feed
Day 8
S :-
Patient is having resting tremors
Altered behavior
Fever spikes
Delayed speech
O:-
Pt is conscious
Bp:-130/70
Pr:-110 bpm
Cvs:-s1s2+
R/s:-BLAE +
P/A:- soft , non tender spleenomegaly
CNS:- NAD
Kerning sign positive
A:-BICYTOPENIA UNDER EVALUATION(2 to malignancy? infection? )
WITH
COMMUNITY ACQUIRED PNEUMONIA WITH ESSENTIAL TREMORS WITH
MODERATE SPLEENOMEGALY
ACUTE SYMPTOMATIC HYPONATREMIA 2 TO SIADH?
ALTERED SENSORIUM 2 TO HYPONATREMIA? MENINGITIS?
P:-
Riley's tube
Foleys catheter
IVF 3% Nacl at 10ml/hr
INJ MEROPENUM 500 mg IV/BD
INJ OPTINEURON 1 AMP IN 100 ml NS/IV/OD
INJ NEOMOL 1 gm IV/SOS
TAB DOLO
Temperature charting
Vital monitoring
Ryles feed
Day 9
S :-
Patient is having resting tremors
Altered behavior
Fever spikes
Delayed speech
O:-
Pt is conscious
Bp:-110/60
Pr:-120 bpm
Cvs:-s1s2+
R/s:-BLAE +
P/A:- soft , non tender spleenomegaly
CNS:- NAD
Kerning sign positive
A:-BICYTOPENIA UNDER EVALUATION
WITH PLASMA CELL DYSCRCIA
COMMUNITY ACQUIRED PNEUMONIA WITH ESSENTIAL TREMORS WITH
MODERATE SPLEENOMEGALY
ACUTE SYMPTOMATIC HYPONATREMIA 2 TO SIADH?
ALTERED SENSORIUM 2 TO HYPONATREMIA? MENINGITIS?
P:-
Riley's tube
Foleys catheter
IVF 3% Nacl at 10ml/hr
INJ MEROPENUM 500 mg IV/BD
INJ OPTINEURON 1 AMP IN 100 ml NS/IV/OD
INJ NEOMOL 1 gm IV/SOS
TAB DOLO
Temperature charting
Vital monitoring
Ryles feed
DISCHARGE SUMMARY
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