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Pathology

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CHRONIC LEUKEMIA By Munukutla Sai Mythili 88     Shwetha Mummadi 87 INTRODUCTION Leukemia is cancer that starts in the blood-forming cells of the bone marrow. When one of these cells changes and becomes a leukemia cell, it no longer matures the way it should and grows out of control. Often, it divides to make new cells faster than normal. Leukemia cells also don't die when they should. This allows them to build up in the bone marrow, crowding out normal cells. At some point, leukemia cells leave the bone marrow and spill into the bloodstream. This increases the number of white blood cells in the blood. Once in the blood, leukemia cells can spread to other organs, where they can prevent other cells in the body from functioning normally. Leukemia is different from other types of cancer that start in organs like the lungs, colon, or breast and then spread to the bone marrow. Cancers that start elsewhere and then spread to the bone marrow are not leukemia. What is a chronic leukem...
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A CASE OF A 61 YEAR OLD MAN WITH BICYTOPENIA UNDER EVALUATION

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This is an online e log book to discuss our patient’s de- identified health data shared after taking his/her/guardian’s signed informed consent. Here we discuss our individual patient’s problems through series of inputs from available global online community of experts with an aim to solve those patient’s clinical problems with collective current best evidence based inputs. This e-log book reflects my patient centered online portfolio and your valuable inputs on the comments is welcome.” A 61 year old male resident of Ramulapeta,yadadri dist who is a daily wage labourer in construction work came to the hospital with complaint of CHIEF COMPLAINTS Dry cough since 10 days  Dragging pain towards the finger tips since 10 days Lower back pain since 10 days Shortness of breath Grade 2 -grade 3 Chest pain near heart since 10 days   HISTORY OF PRESENTING ILLNESS PATIENT WAS APPARENTLY ASYMPTOMATIC 3 YEAR AGO WHEN  He noticed involuntary movements of upper right limb at rest and de...
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critical appraisal

  A CRITICAL APPRAISAL ON THE ARTICLE       ''  Clinical outcomes in vaccinated individuals hospitalized with Delta variant of SARS-CoV-2 '' OBJECTIVES: TO IDENTIFY THE TYPE OF STUDY AND TO WRITE A CRITICAL APPRAISAL BY USING THE HARVARD STYLE CITATION AS A GUIDE FROM THE CRITICAL APPRAISAL SKILLS PROGRAM [ Microsoft Word - CASP Cohort Study Checklist 2018_DRAFT.docx (b-cdn.net) ] To start with let us first discuss what is a cohort study A COHORT STUDY : The word cohort means a group of people. These types of studies look at groups of people. They can be forward-looking (prospective) or backward-looking (retrospective). Prospective” studies are planned in advance and carried out over a future period of time. Retrospective cohort studies look at data that already exist and try to identify risk factors for particular conditions. Interpretations are limited because the researchers cannot go back and gather missing data. APPRAISAL: Research and Clinical study ...
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